Cruises from Vancouver to the Panama Canal & Central America

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Cruises from Vancouver to the Panama Canal & Central America

We found you 7 cruises

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Sapphire Princess (Photo: Princess Cruises)
Sapphire Princess
Sapphire Princess Cabins
Sapphire Princess
Sapphire Princess Dining
Sapphire Princess
Sapphire Princess Activity/Entertainment
Sapphire Princess
Sapphire Princess
Sapphire Princess

20 Nights

Transcanal Cruise

Port: Vancouver • Victoria • San Francisco • Puerto Vallarta • Puerto Quetzal • Puntarenas +4 more

1,020 reviews
Sep 24, 2024
Princess Cruises
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Cruise Critic Favorite

21 Nights

Panama Canal

Port: Vancouver • San Francisco • San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas +7 more

964 reviews
Sep 29, 2024
Holland America Line
Holland America Line
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Cruise Critic Favorite

23 Nights

Transcanal Cruise

Port: Vancouver • San Francisco • San Diego • Santa Barbara • Los Angeles • Puerto Vallarta +7 more

1,032 reviews
Oct 21, 2025
Princess Cruises
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Eurodam
Eurodam
Eurodam Cabins
Eurodam
Eurodam Dining
Eurodam
Eurodam Activity/Entertainment
Eurodam
Eurodam
Eurodam

20 Nights

Panama Canal

Port: Vancouver • Santa Barbara • San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas +6 more

1,201 reviews
Oct 6, 2024
Holland America Line
Holland America Line
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28 Nights

Panama Canal & Eastern Caribbean

Port: Vancouver • San Francisco • San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas +12 more

964 reviews
Sep 29, 2024
Holland America Line
Holland America Line
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23 Nights

Transcanal Cruise

Port: Vancouver • San Francisco • Isla Santa Catalina • San Diego • Los Angeles • Puerto Vallarta +7 more

2,772 reviews
Sep 23, 2025
Princess Cruises
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21 Nights

Panama Canal

Port: Vancouver • Santa Barbara • San Diego • Puerto Vallarta • Huatulco • Puerto Chiapas +7 more

1,201 reviews
Oct 5, 2025
Holland America Line
Holland America Line
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